Grey Theory Based Analysis of Factors Affecting Cellular Uptake in Nano-particle Drug System

Abstract

The Grey correlation degree among the cellular uptake and the features of drug particle is studied, the concerned features include the shape, size, ζ- potential of the drug particle. The grey correlation degrees for above factors are calculated and analyzed on basis of some experimental data from available literature. The results showed that the effect of surface ζ-potential is the most significant in the process of cellular uptake, followed by the factor of the particle shape, while the effect of particle size sits the third one.